Active Multi-Center Clinical Trials in China

Multiple Myeloma · Active Clinical Trials

As of 2026-10-21, the full China registry snapshot contains 64 active multiple myeloma interventional trials across 31 provincial-level regions and 316 China study centres, see landscape index. The list below provides peer-reviewed published English translations and can be filtered by modality, target, phase, and province.

Notice for International Patients

These records are provided for research-information purposes. An English summary does not mean that the clinical trial accepts international patients. Eligibility, language requirements, residence requirements and long-term follow-up must be confirmed directly with the clinical trial team. Original registry filings remain in Chinese. For a non-trial route, see independent guide to CAR-T in China.

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Found 14 active clinical trials(15 matching total)

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Target population synthesized by CMDN from public trial summaries, not official CDE registry verbatim.
RecruitingPhase 1NCT06644118

An Early Exploratory Clinical Study of OL-101 Injection in Patients with Relapsed or Refractory Multiple Myeloma

Locations & Centers

Beijing Gobroad Hospital

Target / Modality

Dual-target CAR-T cell therapy targeting GPRC5D and BCMA

Relapsed/refractory
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RecruitingPhase 2CTR20232951

A Phase I/II Clinical Study of GC012F Injection in the Treatment of Relapsed/Refractory Multiple Myeloma

Locations & Centers

The First Affiliated Hospital, Zhejiang University School of Medicine、Renji Hospital, Shanghai Jiao Tong University School of Medicine、Second Affiliated Hospital of Naval Medical University (Shanghai Changzheng Hospital) 等 10 家

Target / Modality

CAR-T targeting both BCMA and CD19

Relapsed/refractory
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RecruitingPhase 1TM20260016

A Phase I Study of In Vivo CAR-T Therapy for Advanced Malignant Tumors (Multiple Myeloma, Lymphoma, Leukemia, Solid Tumors)

Locations & Centers

Cancer Hospital, Chinese Academy of Medical Sciences

Target / Modality

In situ (in vivo) CAR-T cell therapy targeting multiple targets including BCMA/GPRC5D/DLL3/FcRH5

Relapsed/refractory
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RecruitingPhase 2CTR20233309

A Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Preliminary Efficacy, and Pharmacokinetic Characteristics of KQ-2003 CAR-T Cells in Patients with Relapsed/Refractory Multiple Myeloma

Locations & Centers

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences、The First Affiliated Hospital of Nanchang University、Peking University First Hospital 等 10 家

Target / Modality

Autologous BCMA/CD19 dual-targeting CAR-T

Relapsed/refractory
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RecruitingPhase 2CTR20230238

A Phase II, Open-label, Single-arm, Multicenter Clinical Study Evaluating the Efficacy and Safety of BCMA-targeted Chimeric Antigen Receptor T-cell Injection (CART-BCMA) in Patients with Relapsed/Refractory Multiple Myeloma

Locations & Centers

The First Affiliated Hospital, Zhejiang University School of Medicine、Union Hospital, Tongji Medical College, Huazhong University of Science and Technology、Beijing Jishuitan Hospital 等 25 家

Target / Modality

BCMA-targeted CAR-T cell therapy

Relapsed/refractory
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RecruitingPhase 3CTR20241656

A Randomized Controlled Phase III Clinical Study of Equecabtagene Autoleucel Injection in Patients with Lenalidomide-Refractory Relapsed/Refractory Multiple Myeloma (RRMM)

Locations & Centers

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences、The First Affiliated Hospital, Zhejiang University School of Medicine、Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 等 28 家

Target / Modality

CAR-T

Relapsed/refractory
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RecruitingPhase 1CTR20243438

A Phase I Clinical Study of CBG002 CAR-T Cell Injection in Patients with Relapsed or Refractory Multiple Myeloma

Locations & Centers

The First Affiliated Hospital, Zhejiang University School of Medicine、Union Hospital, Tongji Medical College, Huazhong University of Science and Technology、Sun Yat-sen University Cancer Center

Target / Modality

BCMA-targeting CAR-T cell therapy

Relapsed/refractory
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RecruitingPhase 2

A Clinical Study on the Safety, Tolerability, and Preliminary Efficacy of CR-2011 in Relapsed/Refractory Multiple Myeloma

Locations & Centers

Cancer Hospital Chinese Academy of Medical Sciences

Target / Modality

In vivo chimeric antigen receptor T-cell (CAR-T) therapy targeting BCMA (based on mRNA-LNP technology)

Relapsed/refractory
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RecruitingClinical studyNCT07622862

An Early Exploratory Clinical Study Evaluating the Safety, Tolerability, and Preliminary Efficacy of BCMA/GPRC5D Dual-Targeted Allogeneic Universal CAR-T Cell Injection (DQ1001) in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

Locations & Centers

Zhongshan Hospital, Xiamen University

Target / Modality

Allogeneic universal CAR-T targeting BCMA/GPRC5D

Relapsed/refractory
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RecruitingPhase 1CTR20240189

A Clinical Study of the Safety, Tolerability, and Preliminary Efficacy of SWK001 in Patients with Relapsed or Refractory Multiple Myeloma

Locations & Centers

The First Affiliated Hospital of USTC

Target / Modality

Autologous BCMA/CD19 dual-targeting CAR-T

Relapsed/refractory
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RecruitingPhase 1

An Early Exploratory Clinical Study on the Safety and Efficacy of KSVCBD Injection in the Treatment of CD19- and/or BCMA-Positive B-Cell Malignancies

Locations & Centers

Chinese PLA General Hospital (301 Hospital)

Target / Modality

CD19, BCMA dual-target in vivo CAR-T

Relapsed/refractory
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RecruitingPhase 2CTR20232814

An Open-Label, Multicenter Clinical Study Evaluating the Safety, Pharmacokinetics, and Efficacy of OriCAR-017 in Participants with Relapsed/Refractory Multiple Myeloma (MERCURY)

Locations & Centers

The First Affiliated Hospital, Zhejiang University School of Medicine、Shanghai Tongji Hospital、Jiangsu Province Hospital 等 8 家

Target / Modality

GPRC5D-targeted CAR-T

Relapsed/refractory
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RecruitingClinical studyNCT07715630

In Vivo-Generated PICX Chimeric Antigen Receptor T-cell (CAR-T) Therapy for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)

Locations & Centers

The 920th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army

Target / Modality

Relapsed/refractory multiple myeloma (RRMM)

Relapsed/refractory
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RecruitingPhase 2CTR20221467

A Phase Ib/II Clinical Study of CBM.BCMA Chimeric Antigen Receptor T-cell Injection (C-CAR088) in the Treatment of Patients with Relapsed or Refractory Multiple Myeloma

Locations & Centers

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (Tianjin Institute of Hematology)

Target / Modality

Autologous anti-BCMA CAR-T

Relapsed/refractory
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TerminatedPhase 1CTR20210564

A Phase I Clinical Study of Chimeric Antigen Receptor T-Cell (C-4-29) Formulation for the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)

Locations & Centers

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology、West China Hospital, Sichuan University、Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences

Target / Modality

Autologous anti-BCMA CAR-T

Relapsed/refractory
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