Notice for International Patients & Caregivers

English summary does not mean the trial enrolls international patients. Multiple myeloma interventional clinical trials in China typically require valid Chinese resident identity/national healthcare insurance and strict adherence to China's Human Genetic Resources Administration regulations.

Therapy Focus
Snapshot: 2026-09-04

Monoclonal Antibodies Active Trials in China

As of 2026-09-04, there are 18 active clinical trials investigating Monoclonal Antibodies for multiple myeloma across 29 provinces and 217 study centers in China. Monoclonal antibodies bind a single antigen on the myeloma cell surface — CD38 being the dominant target in China — and eliminate tumour cells through antibody-dependent cytotoxicity and complement activation. They are a common backbone in both frontline and relapsed regimens.

Active Trials
18
Provinces
29
Centers
217

Active Studies (18)

Population synthesized by CMDN

Showing 4 published English records of 18 registry trials.

Phase IIICTR20253414
Recruiting

A Randomized, Controlled, Double-Blind, Multicenter Phase III Clinical Trial Evaluating the Efficacy and Safety of SG301 Injection Combined with Pomalidomide and Dexamethasone Versus Placebo Combined with Pomalidomide and Dexamethasone in the Treatment of Relapsed/Refractory Multiple Myeloma (RRMM)

Target Population: Relapsed/refractory
Target: Novel monoclonal antibody targeting CD38
Study Sites: The First Affiliated Hospital of Soochow University、Beijing Chaoyang Hospital, Capital Medical University、Union Hospital, Tongji Medical College, Huazhong University of Science and Technology、Tianjin Medical University Cancer Institute & Hospital 等 78 家中心
Phase ICTR20254167
Recruiting

A Randomized, Double-Blind, Parallel-Controlled Study Comparing the Pharmacokinetics, Safety, Tolerability, and Immunogenicity of JY43 and Darzalex® in Healthy Male Participants

Target Population: Healthy volunteer
Target: Daratumumab biosimilar (monoclonal antibody)
Study Sites: Beijing Gobroad Hospital、PKU Healthcare Luzhong Hospital
Phase ICTR20260785
Recruiting

A Randomized, Double-Blind, Parallel-Controlled Phase I Study Comparing the Pharmacokinetic Characteristics, Safety, Tolerability, and Immunogenicity of HLX15-SC Versus DARZALEX FASPRO Combined with Lenalidomide-Dexamethasone (Rd) in Patients with Transplant-Ineligible Newly Diagnosed Multiple Myeloma

Target Population: Newly diagnosed
Target: Recombinant fully human monoclonal antibody targeting CD38
Study Sites: Zhongshan Hospital Affiliated to Fudan University、Peking University Third Hospital、Guangzhou First People's Hospital、The Third Hospital of Hebei Medical University 等 66 家中心
Phase ICTR20260125
Recruiting

A Phase I, Open-label, Multicenter Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of HL17 in Participants with Relapsed or Refractory Multiple Myeloma

Target Population: Relapsed/refractory
Target: Recombinant anti-BCMA and CD3 bispecific antibody injection
Study Sites: PKU Healthcare Luzhong Hospital