Notice for International Patients & Caregivers

English summary does not mean the trial enrolls international patients. Multiple myeloma interventional clinical trials in China typically require valid Chinese resident identity/national healthcare insurance and strict adherence to China's Human Genetic Resources Administration regulations.

Therapy Focus
Snapshot: 2026-09-04

Oral Small-Molecule Agents Active Trials in China

As of 2026-09-04, there are 9 active clinical trials investigating Oral Small-Molecule Agents for multiple myeloma across 26 provinces and 102 study centers in China. Oral small-molecule agents span CELMoD degraders, BCL-2 inhibitors and HDAC inhibitors. Their oral route suits long-term administration, and they are typically combined with antibodies or immunomodulators to switch mechanism after resistance.

Active Trials
9
Provinces
26
Centers
102

Active Studies (9)

Population synthesized by CMDN

Showing 2 published English records of 9 registry trials.

Phase I/IICTR20254042
Recruiting

A Phase I/II Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of HP-001 Capsules Combined with Dexamethasone in Patients with Relapsed/Refractory Multiple Myeloma

Target Population: Relapsed/refractory
Target: Small-molecule chemical drug
Study Sites: West China Hospital, Sichuan University、Henan Cancer Hospital、Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences、The First Affiliated Hospital, Zhejiang University School of Medicine 等 20 家中心
Phase IIICTR20232917
Recruiting

A Two-Stage, Randomized, Multicenter, Controlled, Open-Label, Phase III Study Comparing Iberdomide Maintenance Therapy with Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplantation (ASCT) in Participants with Newly Diagnosed Multiple Myeloma (NDMM)

Target Population: Newly diagnosed/Maintenance
Target: Oral small-molecule "molecular glue" degrader (next-generation Cereblon E3 ligase modulator [CELMoD])
Study Sites: Peking University People's Hospital、Tongji Medical College of Huazhong University of Science and Technology、Qilu Hospital of Shandong University、Jiangsu Province Hospital 等 37 家中心